ISSN: 2706-8870
Volume 7, Number 2 (2022)
Year Launched: 2016
Journal Menu
■ About The Journal
■ Aims & Scope
■ Editorial Board
■ Article Processing Charge
■ Archive

Metastatic cerebellar tumor from esophageal squamous carcinoma: a case report and review of the literature

Volume 7, Issue 2, April 2022     |     PP. 86-93      |     PDF (435 K)    |     Pub. Date: March 16, 2022
DOI: 10.54647/cm32699    79 Downloads     5218 Views  

Author(s)

Ludovica Cellini, Policlinico Santa Maria Le Scotte, Siena, Italy
Gonçalo Januário, Centro Hospitalar Universitário de Lisboa Central; Hospital de São José, Lisbon, Portugal
Gonçalo Novais, Centro Hospitalar Universitário de Lisboa Central; Hospital de São José, Lisbon, Portugal

Abstract
Esophageal cancer is one of the most fatal malignancies. It is often diagnosed during its advanced stages. Brain metastases, and especially cerebellar ones have been infrequently reported in the Literature. In patients with large cerebellar metastases, surgical removal is still the most effective therapy for improving survival and Karnofsky Performance Score (KFS). Stereotactic Radiosurgery is another treatment option for multiple brain metastases but the improvement in survival was only demonstrated in single metastasis. We report a case of multiple cerebellar metastases from esophageal squamous cell cancer in a 64 years old male, who underwent macroscopic total resection of all lesions.
 Up to date no treatment guidelines exist for esophageal cancer brain metastases. Multimodal therapy including surgery, radiation, and chemotherapy is now generally recommended for treatment of these lesions. Total resection of cerebellar ones should be the aim of surgical therapy, especially if a good KPS is expected.

Keywords
Brain Metastases; Carcinoma; Craniotomy; Total resection; Radiotherapy; Chemotherapy

Cite this paper
Ludovica Cellini, Gonçalo Januário, Gonçalo Novais, Metastatic cerebellar tumor from esophageal squamous carcinoma: a case report and review of the literature , SCIREA Journal of Clinical Medicine. Volume 7, Issue 2, April 2022 | PP. 86-93. 10.54647/cm32699

References

[ 1 ] Epidemiology of esophageal cancer. Yuwei Zhang. World J Gastroenterol. 2013 Sep 14.
[ 2 ] Esophageal Cancer: Risk Factors, Genetic Association, and Treatment. Fang-Liang Huang et al. Asian J Surg. May 2018.
[ 3 ] Esophageal Cancer. Benjamin R. Alsop et al. Gastroenterol Clin North Am. Sep 2016.
[ 4 ] Esophageal Cancer Metastases to Unexpected Sites: A Systematic Review. Osama Shaheen et al. Gastroenterol Res Pract. 2017.
[ 5 ] Surgical treatment of cerebellar metastases. Ali J. Ghods et al. Surg Neurol Int. 2011.
[ 6 ] Retrospective Study of 127 Surgically Treated Patients With Multiple Brain Metastases: Indication, Prognostic Factors, and Outcome. Gabriele Schackert et al. Acta Neurochir (Wien). Mar 2013.
[ 7 ] Brain Metastases from Esophageal Carcinoma: Natural History, Prognostic Factors, and Outcome. Ogawa K. Et al. Cancer. 2002.
[ 8 ] Results and prognostic factors in a consecutive series of 44 operated patients.Pompili A. et al. J Neurooncol. 2008.
[ 9 ] Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO). Riccardo Soffietti et al. Neuro-Oncology. 2017.