ISSN: 2706-8870
Volume 4, Number 6 (2019)
Year Launched: 2016

Group B Streptococcal colonisation among Sri Lankan mothers

Volume 4, Issue 6, December 2019     |     PP. 209-215      |     PDF (382 K)    |     Pub. Date: October 28, 2019
DOI:    241 Downloads     6248 Views  

Author(s)

Dr. H.D.W.S Kudagammana, Medical Microbiologist, Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Peradeniya, Sri Lanka
Dr. R.M.C.J Rathnayaka, Consultant Obstetrician & Gynecologist Dept. of Gynecology & Obstetrics Faculty of Medicine, University of Peradeniya, Sri Lanka
Mr. B.W.M.S.B Weerasooriya, Technical Officer, Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Peradeniya, Sri Lanka
Dr. K.M.A.G Karunathilaka, Medical Officer, Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Peradeniya, Sri Lanka
Mr. J.A.C.N Kumara, Medical Laboratory Scientist, Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Peradeniya, Sri Lanka

Abstract
Knowledge on Group B Streptococcus (GBS) carriage among Sri Lankans is very low compared to other countries of the South Asian region. A descriptive cross-sectional study was carried out to determine GBS colonization among consecutive 50 pregnant mothers at or beyond 35 weeks of gestation at T H Peradeniya attending obstetric clinics. Low vaginal/peri-anal swabs obtained were enriched and sub-cultured on standard media followed by identification and confirmation of GBS using validated microbiology protocols and standard antisera. Of all fifty subjects screened, 10% showed GBS colonization. Our study showed maternal colonization with GBS rate similar to recent data of other South Asian countries.

Keywords
Group B streptococcus, Colonisation, Pregnancy

Cite this paper
Dr. H.D.W.S Kudagammana, Dr. R.M.C.J Rathnayaka, Mr. B.W.M.S.B Weerasooriya, Dr. K.M.A.G Karunathilaka, Mr. J.A.C.N Kumara, Group B Streptococcal colonisation among Sri Lankan mothers , SCIREA Journal of Clinical Medicine. Volume 4, Issue 6, December 2019 | PP. 209-215.

References

[ 1 ] Morven SF, and Carol JB. Streptococcus agalactiae (Group B Streptococcus) in Mandell, Douglas, and Bennett’s Principles of Infectious Diseases. 8th ed. Philadelphia: Elsevier; 2015. p. 3140-48d
[ 2 ] Jennifer RV, Lesley McGee, Stephanie JS. Prevention of Perinatal Group B Streptococcal Disease Revised Guidelines from CDC, 2010 Morbidity and Mortality Weekly Report www.cdc.gov/mmwr November 19, 2010 / Vol. 59 / No. RR-10
[ 3 ] Libster R, Edwards KM, Levent F, Morven S. E, Marcia AR, Castagnini RNDL, Cooper T, Sparks RC, Baker CJ and Shah PE. Long-term outcomes of group B streptococcal meningitis. Pediatrics. 2012;130: p. e8-e15.ar
[ 4 ] Dulmini Nanayakkara, Veranja Liyanapathirana, Chaminda Kandauda, Champika Gihan, Asela Ekanayake and Dinuka Adasooriya, 2018: Maternal vaginal colonization with selected potential pathogens of neonatal sepsis in the era of antimicrobial resistance, a single center experience from Sri Lanka BMC Infectious Diseases18:35https://doi.org/10.1186/s12879-018-3262-y
[ 5 ] Brimil N. Barthell E, Heindrichs V, Kuhn M, Lutticken R and Spellerberg A. 2006: Epidemiology of Streptococcus agalactiae colonization in Germany. The International Journal of Medical Microbiology. 296(1): p. 39 – 44
[ 6 ] Russell NJ, Seale AC, O'Driscoll M, O'Sullivan C, Bianchi-Jassir F, Gonzalez-Guarin J, Lawn JE, Baker CJ, Bartlett L, Cutland C, Gravett MG, Heath PT, Le Doare K, Madhi SA, Rubens CE, Schrag S, Sobanjo-TMA, Vekemans J, Saha, SKM. 2017 GBS Maternal Colonization Investigator Group. Maternal Colonization With Group B Streptococcus and Serotype Distribution Worldwide: Systematic Review and Meta-analyses. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America, 65(suppl_2), S100-S111.
[ 7 ] Phares CR, Lynfield R, Farley MM, Mohle-Boetani J, Harrison LH, Petit S, Craig AS, Schaffner W, Zansky SM, Gershman K, Stefonek KR, Albanese BA, Zell ER, Schuchat A, Schrag SJ. 2008: Active Bacterial Core surveillance/Emerging Infections Program Network. JAMA 299(17):p. 2056-65. doi:10.1001/jama.299.17.2056
[ 8 ] Rodriguez-Grangert J, Alvargonzalez JC, Beradi A, Berner R, Kunze M, Hafnagel M, Melin P, Decheve A, Orefici G, Poyert C, Telford J, Efstration A, Killian M, Krizova P, Baldassari L, Spellerberg B, Puertas A and Fraile RM. 2012: Prevention of group B streptococcal neonatal disease revisited. The DEVANI European project. European Journal of Clinical Microbiology & Infectious Diseases, 31(9): p. 2097–104
[ 9 ] http://www.who.int/immunization/newsroom/press/news_group_b_strep_stillbirths_infant_deaths_2017/en/#.W_gIZom_PFc.email last viewed 2018 Nov